CD42b-APC (クローン: SZ2, 50テスト)
Product No:B13980
CD42b抗原（GPIbα）は135kDaの膜糖タンパク質で、CD42c（GP1bβ）とジスルフィド結合して160kDaの膜タンパク質（GP1b）を形成します。GP1bは、GPIX（CD42）及びGPV（CD42d）と非共有結合的に複合体を形成します。この抗原は、血小板や巨核球に存在し、血管と扁桃の内皮細胞でも報告があります。CD42 a-d複合体は von Willebrand 因子のレセプタであり、von Willebrand 因子依存性の接着レセプタとしても知られています。
¥52,500 (税抜) List Price - ¥52,500
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製品仕様
| Target Species | Human |
| Specificity | CD42b |
| Other Names | CD42b, glycoprotein GPIb-a, gpIb, GPIb-a, platelet glycoprotein GPIb-a |
| Fluorochrome | APC |
| Regulatory Status | ASR |
| Size | 0.5 mL |
| Format | Liquid |
| Flow Product Line | IOTest |
| Clone | SZ2 |
| Isotype | IgG1 Mouse |
| Clone Description | The SZ2 monoclonal antibody prevents the ristocetin-dependent binding of von Willebrand's factor to platelets and inhibits ristocetin-induced platelet agglutination. Platelet aggregation induced by type I collagen and Platelet Activating Factor (PAF) is also inhibited. The SZ2 antibody immunoprecipitates the components of the GPIb complex. It may also be used in Western blot. |
| Volume | 0.5 mL |
