CD49b-UNLB (クローン: Gi9, 0.2 mg)
Product No:IM0717
CD49b抗原（GPIa）は、150kDaのインテグリン α-2鎖で、インテグリン β-1（CD29、GPIIa）と非共有結合的に会合して、VLA-2（very late activation antigen）複合体を形成します。この複合体は、コラーゲンとの細胞接着に関与しています。 血小板及び活性化したT細胞と胸腺細胞に発現します。
¥60,900 (税抜) List Price - ¥60,900
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製品仕様
| Target Species | Human |
| Specificity | CD49b |
| Other Names | CD49b, gpIa, Integrin alpha 2 chain, Integrin alpha2-chain, platelet gpla, VLA-2, VLA-alpha 2-chain |
| Fluorochrome | UNLB |
| Regulatory Status | RUO |
| Size | 0.2 mg |
| Format | Freeze-dried |
| Flow Product Line | - |
| Clone | Gi9 |
| Isotype | IgG1 Mouse |
| Clone Description | The Gi9 antibody reacts with the molecule carrying the Br(a) as well as the Br(b) alloantigen. This antibody inhibits the adhesion of platelets to collagen. It detects human alloantibodies (anti-Br a,b) against VLA-2 by MAIPA assay. Gi9 was used as a CD49b reference monoclonal antibody during the HLDA 6. Gi9 reacts with platelets and weakly with monocytes. It also stains most adherent cell lines and T lymphocytes in culture. |
